Business Resources

Biological Process Development Facility (BPDF) – University of Nebraska Lincoln

The Biological Process Development Facility (BPDF) at the University of Nebraska offers biopharmaceutical process development and biomanufacturing services that transition discoveries into early phase clinical trials.


BPDF capabilities include:

  • Master and working cell banks

  • Upstream and downstream process development

  • Stability testing services

  • Analytical method development and qualification

  • Microbial manufacture of biologics

Fermentation processes focus on optimizing and controlling high cell-density fermentations of Pichia pastorisSaccharomyces cerevisiae, and Escherichia coli for recombinant protein production. Activities are governed by a rigorous quality system as well as regulatory support.

The BPDF has produced a wide range of biologics—including vaccines, recombinant proteins, gene therapies and other biotherapeutics—in partnership with government agencies, biotechnology companies, academic researchers, and non-profit organizations. The BPDF applies decades of expertise and experience to developing scalable and reproducible cGMP manufacturing processes.

Services Provided

Libraries and Research Organizations

  • Business Research Resources

Product Development

  • Product Design and Development
  • R & D Support

Manufacturing, High Tech, Life Sciences Development

  • Manufacturing Development
  • Life Sciences Development

Internship Programs and Student Services

  • Student Research Projects
Contact Information
Biological Process Development Facility
304 Othmer Hall
Lincoln, NE 68588