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Biological Process Development Facility (BPDF) – University of Nebraska Lincoln

The Biological Process Development Facility (BPDF) at the University of Nebraska offers biopharmaceutical process development and biomanufacturing services that transition discoveries into early phase clinical trials.

About

BPDF capabilities include:

  • Master and working cell banks

  • Upstream and downstream process development

  • Stability testing services

  • Analytical method development and qualification

  • Microbial manufacture of biologics

Fermentation processes focus on optimizing and controlling high cell-density fermentations of Pichia pastoris, Saccharomyces cerevisiae, and Escherichia coli for recombinant protein production. Activities are governed by a rigorous quality system as well as regulatory support.

The BPDF has produced a wide range of biologics—including vaccines, recombinant proteins, gene therapies and other biotherapeutics—in partnership with government agencies, biotechnology companies, academic researchers, and non-profit organizations. The BPDF applies decades of expertise and experience to developing scalable and reproducible cGMP manufacturing processes.

Services Provided

Libraries and Research Organizations

  • Business Research Resources

Product Development

  • Product Design and Development
  • R & D Support

Manufacturing, High Tech, Life Sciences Development

  • Life Sciences Development
  • Manufacturing Development

Internship Programs and Student Services

  • Student Research Projects
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Contact Information
Biological Process Development Facility
Address
304 Othmer Hall
Lincoln, NE 68588
Phone
(402) 472-1983
Website
https://engineering.unl.edu/bpdf/
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